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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I

Fig. 4

Inhibitory effect of ME on oral tumor growth in an orthotopic mouse model. a Representative BLI signal in control and ME -treated mice bearing orthotopic SCC-9 oral tumors which were treated with vehicle (corn oil), or ME (120 mg/kg, 5 times per week for 6 weeks starting 1 week after tumor inoculation). b Representative photographs of tumors from control and ME-treated mice. c BLI signal intensity of oral orthotopic SCC-9 tumors over time. d Effects of ME on EPR signals of oral orthotopic tumors harvested at the time of sacrifice.**P < 0.01

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