Fig. 4From: Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex IInhibitory effect of ME on oral tumor growth in an orthotopic mouse model. a Representative BLI signal in control and ME -treated mice bearing orthotopic SCC-9 oral tumors which were treated with vehicle (corn oil), or ME (120 mg/kg, 5 times per week for 6 weeks starting 1 week after tumor inoculation). b Representative photographs of tumors from control and ME-treated mice. c BLI signal intensity of oral orthotopic SCC-9 tumors over time. d Effects of ME on EPR signals of oral orthotopic tumors harvested at the time of sacrifice.**P < 0.01Back to article page