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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling

Fig. 6

XIAOPI formula inhibits the recruitment of HSPCs and differentiation into MDSCs. a-b The HSPCs populations in the bone marrow were detected by flow cytometry. XIAOPI formula treatment blocked TAMs-induced HSPCs elevation, but was relieved by CXCL1 overexpression. c-d The MDSCs populations in the lung tissues were detected by flow cytometry. XIAOPI formula treatment remarkably inhibited CD11b+/Gr1+ MDSCs accumulation in the lung tissues from the 2nd to 4th weeks, but was relieved by CXCL1 overexpression in TAMs. (The results were represented as mean values ± SD, *P < 0.05, **P < 0.01)

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Cell Communication and Signaling

ISSN: 1478-811X