Table 2 Univariate and Multivariate analysis of factors associated with OS

Age (≥60 vs. < 60)

1.224

0.893–1.678

0.208

Gender (female vs. male)

0.747

0.504–1.108

0.147

Smoking status (smokers vs. non-smokers)

1.192

0.867–1.639

0.280

Tumor size(≥3 cm vs. < 3 cm)

1.859

1.307–2.645

0.001

1.426

0.988–2.057

0.058

Tumor stage (III-IV vs. I-II)

2.420

1.760–3.327

< 0.001

2.233

1.606–3.105

< 0.001

TET3 level (high vs. low)

1.510

1.091–2.090

0.013

1.479

1.066–2.051

0.019