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Table 1 Correlation between TET3 and clinicopathological features in 299 ESCC patients

From: Epigenetic induction of tumor stemness via the lipopolysaccharide-TET3-HOXB2 signaling axis in esophageal squamous cell carcinoma

Variables

NO. of patients

TET3 expression

P

Low

High

Age

  < 60

156

72(46)

84(54)

0.627

  ≥ 60

143

62(43)

81(57)

Gender

 Male

231

95(41)

136(59)

0.018

 Female

68

39(57)

29(43)

Smoking status

 Smokers

163

68(42)

95(58)

0.238

 Non-smokers

136

66(49)

70(51)

Differentiation

 I

19

13(68)

6(32)

0.033

 II-III

280

121(43)

159(57)

Tumor invasion depth

 T1–2

117

58(50)

59(50)

0.185

 T3–4

182

76(42)

106(58)

Tumor stage

 I-II

189

85(45)

104(55)

0.943

 III-IV

110

49(45)

61(55)

Lymph node metastasis

 Yes

178

86(48)

92(52)

0.140

 No

121

48(40)

73(60)

Tumor size

  < 3 cm

110

57(52)

53(48)

0.063

  ≥ 3 cm

189

77(41)

112(59)