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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Expression of apoptosis repressor with caspase recruitment domain (ARC) in familial adenomatous polyposis (FAP) adenomas and its correlation with DNA mismatch repair proteins, p53, Bcl-2, COX-2 and beta-catenin

Fig. 3

Representative examples of p53 results. Only 16% of FAP adenomas exhibited strong overexpression of p53 (score 2; c). However, overexpression of p53 correlated with nuclear ARC expression (p = 0.012). In most tissue slices, expression of p53 was limited to 10–75% of FAP adenoma cells (score 1; b). In 13%, no or weak p53 expression was detected (score 0; a)

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Cell Communication and Signaling

ISSN: 1478-811X