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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: mTOR-dependent dysregulation of autophagy contributes to the retinal ganglion cell loss in streptozotocin-induced diabetic retinopathy

Fig. 7

The effects of short-term hyperglycemia on STZ-mouse retina are reversible by glycemic control. a The expression of mTOR related proteins, GLUT1 and β-actin detected by Western blot. b Immuno-co-staining for pmTOR S2448 (green) and GLUT1 (red) of the retina from normal and 1-month diabetic mice treated with either phlorizin or rapamycin. c Immuno-co-staining for pmTOR S2448 (green) and GFAP (red) of the retina from normal and 1-month diabetic mice treated with either phlorizin or rapamycin (a). Nuclei were counter-stained with Hoechst 33,342 (blue). GCL, ganglion cell layer; INL, inner nuclear layer; ONL, outer nuclear layer; Scale bar: 50 µm

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