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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Inflammasome activation controlled by the interplay between post-translational modifications: emerging drug target opportunities

Fig. 3

ASC/PYCARD PTMs and the enzymes responsible for their regulation. Empirically validated enzymes which are responsible for the PTM regulation of ASC/PYCARD. “+” indicates that the enzyme promotes the activation of ASC oligomerization, while “−” indicates repression of its function. Amino acid residues shown above refer to human ASC, those in brackets refer to mouse ASC residues

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