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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: PSF functions as a repressor of hypoxia-induced angiogenesis by promoting mitochondrial function

Fig. 4

PSF affected the mitochondrial bioenergetic and glycolytic profiles under hypoxic conditions. After exposure to hypoxia, the mitochondrial respiration and glycolytic functions in PSF-treated or vehicle HRMECs were measured using Seahorse analysis. a Representative traces identifying the pattern of OCR in mitochondria stress tests. b Basal OCR, c ATP production, d maximal respiration and e spare respiratory capacity in ectopic PSF cells. f The indicative curve for the average extracellular acidification rate (ECAR) within glycolysis stress assays, g glycolysis, h glycolytic capacity, and i the reservation of glycolysis were indicated.*P < 0.05

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