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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: The association between RGS4 and choline in cardiac fibrosis

Fig. 6

RGS4 antagonized anti-cardiac fibrosis effect of choline through TGF-β1/Smad and MAPK signaling. a The protein levels of TGF-β1 and b p-Smad2/3, central members of TGF-β1/Smad signaling, was assessed by western blot analysis. n = 4 or n = 5. c The protein levels of p-p38 and d p-ERK1/2, key members of MAPK signaling, was assessed by western blot analysis. TGF-β1 + Choline + pcDNA3.1served as a negative control. n = 6 or n = 4. *p < 0.05, **p < 0.01 versus Control, #p < 0.05, ##p < 0.01, ###p < 0.001 versus TGF-β1, &p < 0.05 versus TGF-β1 + Choline + pcDNA3.1

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