Fig. 2

HRD1 elicited an anti-Warburg effect that inhibited the growth, migration, and invasion of breast cancer cells. a MCF-7 and MDA-MB-231 cells stably expressing HRD1 were treated with 2-deoxyglucose (2-DG; 5 mmol/L) for 72 h, and then cell proliferation was measured using CCK-8 assays. b MCF-7 and MDA-MB-231 cells stably expressing HRD1 were treated with 2-DG (5 mmol/L) for 3 weeks, and then colony-formation assay were performed. c, d MCF-7 and MDA-MB-231 cells stably expressing HRD1 were treated with 2-DG (5 mmol/L) for 48 h, and then the migration and invasion assays were performed