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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Proteomics identifies differences in fibrotic potential of extracellular vesicles from human tendon and muscle fibroblasts

Fig. 5

Identification of tendon EV-enriched proteins. a Venn diagram showing the number of proteins with > 2-fold mean differential abundance in TenX when compared to MyoX (90 proteins) and in TenX when compared to FibX (68 proteins), with 10 proteins in common. b Venn diagram showing the number of proteins with > − 2-fold mean differential abundance in TenX when compared to FibX (21 proteins) and in MyoX when compared to FibX (83 proteins), with 9 proteins in common. See Supplementary Data 9 for full list of proteins (FDR < 0.01). c Plots showing the log transformed intensities of the 10 commonly over abundant TenX proteins. AMembrane-localised proteins: ANTXR2, PMCA4 (ATP2B4), PTGFRN, syntaxin-4 and syntaxin-7. d Plots showing the log transformed intensities of the 9 commonly over abundant FibX proteins. BMembrane-localised protein: CD73 (NT5E). *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001. See Supplementary Data 6 for all adjusted p-values from DESeq2 analysis

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Cell Communication and Signaling

ISSN: 1478-811X