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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Receptor-interacting protein kinase 1 is a key mediator in TLR3 ligand and Smac mimetic-induced cell death and suppresses TLR3 ligand-promoted invasion in cholangiocarcinoma

Fig. 1

TLR3 is frequently expressed in primary CCA tissues and cell lines. a The representative cytoplasmic TLR3 immunostaining in tumor area and adjacent normal tissues. Black arrowheads indicate bile ducts.b The median of H-score of staining in CCA primary tissues (tumor tissues and adjacent). The difference between the median of H-score of tumor and adjacent tissues was calculated by one-way ANOVA and presented as p-value. c Distribution of TLR3 expression according to H-score of tumor area and adjacent area. d Protein expression of TLR3 was analyzed in 6 different human CCA cell lines and an immortalized human cholangiocyte cell line, MMNK1 using Western blot analysis and β-actin was served as loading control

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