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Table 2 Univariate and multivariate analysis of overall survival in CRC patients. (Cox proportional hazards regression model)

From: JARID1B promotes colorectal cancer proliferation and Wnt/β-catenin signaling via decreasing CDX2 level

Parameters (130 CRC patients)a

Univariate analysis

Multivariate analysis

HR

95%CI

p value

HR

95%CI

p value

Age (60/> 60)

0.70

0.34–1.41

0.32

   

Gender (Male/Female)

1.13

0.57–2.22

0.73

   

Histologic grade (well/poor)

0.66

0.29–1.51

0.33

   

Tumor size (cm) (< 5/5)

1.78

0.90–3.51

0.10

   

CEA (ng/ml) (< 5/5)

1.09

0.75–1.60

0.64

   

Lymphatic invasion (Positive/Negative)

1.95

1.04–3.67

0.04*

1.52

0.52–4.43

0.03*

Distant metastasis (Positive/Negative)

2.03

1.09–3.78

0.03*

1.65

0.62–4.38

0.01**

T classification (T3 + T4/T1 + T2)

2.65

1.20–5.85

0.02*

1.80

0.67–4.84

0.02*

TNM (III, IV/I, II)

2.49

1.24–5.00

0.01**

2.12

1.13–3.98

0.02*

JARID1B protein expression (High/Low)

2.29

1.41–3.73

0.00**

2.53

1.50–4.27

0.00**

  1. aImmunohistochemical results of 130 paraffin-embedded tissues from December 2012 to December 2017, *p ≤ 0.05,**p ≤ 0.01