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Table 2 Univariate and multivariate analysis of overall survival in CRC patients. (Cox proportional hazards regression model)

From: JARID1B promotes colorectal cancer proliferation and Wnt/β-catenin signaling via decreasing CDX2 level

Parameters (130 CRC patients)a Univariate analysis Multivariate analysis
HR 95%CI p value HR 95%CI p value
Age (60/> 60) 0.70 0.34–1.41 0.32    
Gender (Male/Female) 1.13 0.57–2.22 0.73    
Histologic grade (well/poor) 0.66 0.29–1.51 0.33    
Tumor size (cm) (< 5/5) 1.78 0.90–3.51 0.10    
CEA (ng/ml) (< 5/5) 1.09 0.75–1.60 0.64    
Lymphatic invasion (Positive/Negative) 1.95 1.04–3.67 0.04* 1.52 0.52–4.43 0.03*
Distant metastasis (Positive/Negative) 2.03 1.09–3.78 0.03* 1.65 0.62–4.38 0.01**
T classification (T3 + T4/T1 + T2) 2.65 1.20–5.85 0.02* 1.80 0.67–4.84 0.02*
TNM (III, IV/I, II) 2.49 1.24–5.00 0.01** 2.12 1.13–3.98 0.02*
JARID1B protein expression (High/Low) 2.29 1.41–3.73 0.00** 2.53 1.50–4.27 0.00**
  1. aImmunohistochemical results of 130 paraffin-embedded tissues from December 2012 to December 2017, *p ≤ 0.05,**p ≤ 0.01