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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Intrinsic disorder is an essential characteristic of components in the conserved circadian circuit

Fig. 2

Computational Analysis Demonstrates Disorder in the Negative-Arm Constituents. Plots of the disordered propensity scores vs the primary amino acid sequence of the negative-arm components from Murine, Neurospora, and Drosophila clocks. The propensity scores were calculated using four algorithms, the first three from the PONDR family VLXT (red line), VL3-BA (green line) and VSL2 (purple line) and the last from IUPred2A long (orange line). The mean is plotted as the blue line with the SD distribution shaded in light blue [51,52,53,54]. Any residue scoring 0.5 or higher in the mean calculation was considered toward the percent disorder calculation

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