Fig. 2

H. pylori selectively augments SOCS3 expression.a DCs were infected withH. pylori strain P12 at MOI = 5 or stimulated with E. coli-derived LPS (1 ng/ml) for 4 h. SOCS mRNA expression was measured by qRT-PCR. Dots represent individual donors; the horizontal line in each column indicates the mean value ± SD of one experiment comprising four donors. (N = 4) For statistical analysis, one-way ANOVA with Tukey’s post-hoc test was performed. **p < 0.01, ***p < 0.001 b SOCS expression in H. pylori-negative and H. pylori-positive gastritis patients was determined using a publicly available genomic dataset (GSE5081), which was analyzed using Python. Dots represent individual donors; the horizontal line in each column indicates the mean value ± SD. (N = 16) For statistical analysis, a two-tailed, unpaired t test was performed. *p < 0.05