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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: LncRNAH19 improves insulin resistance in skeletal muscle by regulating heterogeneous nuclear ribonucleoprotein A1

Fig. 3

The effects of H19 on metabolic signaling pathway genes in skeletal muscles and cells. (a) H19 overexpression increased the protein levels of glucose and lipid metabolic genes in skeletal muscles. Representative gel images are presented in the left panel, and quantitative data are in the right panel. (b) H19 overexpression in skeletal muscles increased mRNA of glucose and lipid metabolic genes. H19 overexpression (c) and H19 knockdown (d) in muscle cells influenced mRNA of glucose and lipid metabolic genes. (e) H19 overexpression in muscle cells increased mitochondrial electronic chain complex proteins. n = 6 mice per genotype. Quantification was based on 3 independent experiments. Numbers were the mean ± SD. ***p < 0.001, **p < 0.01, *p < 0.05, n.s, not significant

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