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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Curcumin derivative C212 inhibits Hsp90 and eliminates both growing and quiescent leukemia cells in deep dormancy

Fig. 1

C212 inhibits the growth of a variety of cancer cells.a-h Growing cancer cells seeded in 96-well plates were treated with curcumin and C212, respectively, at the indicated doses for 48 h. Cell growth was measured with MTS assay in leukemia cell lines HL60 and K562 (a and b), colon cancer cell lines HCT116, SW620, and HT29 (c, d, and e), breast cancer cell line MCF-7 (f), gastric cancer cell line SGC7901 (g), and liver cancer cell line HepG2 (h). Error bar, SEM (n = 3); * p < 0.05, ** p < 0.01, *** p < 0.001 (C212 vs. curcumin; see Methods for statistical analysis detail; the same below)

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