Fig. 4
From: Exosomal microRNAs derived from mesenchymal stem cells: cell-to-cell messages
Inter-cellular communications between MSCs and other cell types via EVs. Upper panel: MSCs as the recipient cells. Lower panel: MSCs as the donor cells. Left Panel: MSCs exchange exosomes with recipient cells. Right Panel: Cross talk between MSCs and cancer cells. CTGF: connective tissues growth factor. EVs: extra-cellular vesicles. FGF: fibroblast growth factor. HSP: heat shock protein. IL: interleukin. mRNA: messenger RNA. miRNA or miR: microRNA. MSC: mesenchymal stem cell. PDGF: platelet derived growth factor. PD-L1 programmed death-ligand-1. SMA: smooth muscle actin. TGF: transforming growth factor. VEGF: vascular endothelial growth factor