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Table 1 Clinical features of study subjects

From: Alpha-1 antitrypsin deficient individuals have circulating extracellular vesicles with profibrogenic cargo

Variables

Controls

n = 20

Patients

n = 20

Age

47.0 ± 14.2

60.4 ± 7.7

Gender

 Male (%)

6 (30)

14 (70)

 Female (%)

14 (70)

6 (30)

Smoking History

 Never (%)

4 (20)

12 (60)

 Current (%)

3 (15)

0 (0)

 Past (%)

4 (20)

8 (40)

 No data (%)

9 (45)

0 (0)

 Genotype

MM = 20 (100)

ZZ = 20 (100)

 PASD 3(%)

No biopsy

20 (100)

Fibrosis

 3

No biopsy

6 (30)

 2

 

10 (50)

 1

 

4 (20)

Plasma AAT Levels (μM)

24.7 ± 4.9

13.8 ± 10.9

  1. Data are expressed as mean (SD) or n (percentage)