TY - JOUR AU - Binda, E. AU - Visioli, A. AU - Giani, F. AU - Trivieri, N. AU - Palumbo, O. AU - Restelli, S. PY - 2017 DA - 2017// TI - Wnt5a drives an invasive phenotype in human Glioblastoma stem-like cells JO - Cancer Res VL - 77 UR - https://doi.org/10.1158/0008-5472.CAN-16-1693 DO - 10.1158/0008-5472.CAN-16-1693 ID - Binda2017 ER - TY - JOUR AU - Hayakawa, Y. AU - Ariyama, H. AU - Stancikova, J. AU - Sakitani, K. AU - Asfaha, S. AU - Renz, B. W. PY - 2015 DA - 2015// TI - Mist1 expressing gastric stem cells maintain the Normal and neoplastic gastric epithelium and are supported by a perivascular stem cell niche JO - Cancer Cell VL - 28 UR - https://doi.org/10.1016/j.ccell.2015.10.003 DO - 10.1016/j.ccell.2015.10.003 ID - Hayakawa2015 ER - TY - JOUR AU - Chen, Y. C. AU - Gonzalez, M. E. AU - Burman, B. AU - Zhao, X. AU - Anwar, T. AU - Tran, M. PY - 2019 DA - 2019// TI - Mesenchymal Stem/Stromal Cell Engulfment Reveals Metastatic Advantage in Breast Cancer JO - Cell Reports VL - 27 UR - https://doi.org/10.1016/j.celrep.2019.05.084 DO - 10.1016/j.celrep.2019.05.084 ID - Chen2019 ER - TY - JOUR AU - Merle, P. AU - Monte, S. AU - Kim, M. AU - Herrmann, M. AU - Tanaka, S. AU - Bussche, A. PY - 2004 DA - 2004// TI - Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma JO - Gastroenterology VL - 127 UR - https://doi.org/10.1053/j.gastro.2004.07.009 DO - 10.1053/j.gastro.2004.07.009 ID - Merle2004 ER - TY - JOUR AU - Merle, P. AU - Kim, M. AU - Herrmann, M. AU - Gupte, A. AU - Lefrancois, L. AU - Califano, S. PY - 2005 DA - 2005// TI - Oncogenic role of the frizzled-7/beta-catenin pathway in hepatocellular carcinoma JO - J Hepatol VL - 43 UR - https://doi.org/10.1016/j.jhep.2005.05.018 DO - 10.1016/j.jhep.2005.05.018 ID - Merle2005 ER - TY - JOUR AU - Kim, M. AU - Lee, H. C. AU - Tsedensodnom, O. AU - Hartley, R. AU - Lim, Y. S. AU - Yu, E. PY - 2008 DA - 2008// TI - Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells JO - J Hepatol VL - 48 UR - https://doi.org/10.1016/j.jhep.2007.12.020 DO - 10.1016/j.jhep.2007.12.020 ID - Kim2008 ER - TY - JOUR AU - Yang, L. AU - Wu, X. AU - Wang, Y. AU - Zhang, K. AU - Wu, J. AU - Yuan, Y. C. PY - 2011 DA - 2011// TI - FZD7 has a critical role in cell proliferation in triple negative breast cancer JO - Oncogene VL - 30 UR - https://doi.org/10.1038/onc.2011.145 DO - 10.1038/onc.2011.145 ID - Yang2011 ER - TY - JOUR AU - King, T. D. AU - Suto, M. J. AU - Li, Y. PY - 2012 DA - 2012// TI - The Wnt/beta-catenin signaling pathway: a potential therapeutic target in the treatment of triple negative breast cancer JO - J Cell Biochem VL - 113 UR - https://doi.org/10.1002/jcb.23350 DO - 10.1002/jcb.23350 ID - King2012 ER - TY - JOUR AU - Anastas, J. N. AU - Kulikauskas, R. M. AU - Tamir, T. AU - Rizos, H. AU - Long, G. V. AU - Euw, E. M. PY - 2014 DA - 2014// TI - WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors JO - J Clin Invest VL - 124 UR - https://doi.org/10.1172/JCI70156 DO - 10.1172/JCI70156 ID - Anastas2014 ER - TY - STD TI - Flanagan DJ, Barker N, Costanzo NSD, Mason EA, Gurney A, Meniel VS, et al. Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations. Cancer Res. 2019;79(5):970–81. ID - ref10 ER - TY - JOUR AU - Liu, S. AU - Cong, Y. AU - Wang, D. AU - Sun, Y. AU - Deng, L. AU - Liu, Y. PY - 2014 DA - 2014// TI - Breast cancer stem cells transition between epithelial and mesenchymal states reflective of their normal counterparts JO - Stem Cell Reports VL - 2 UR - https://doi.org/10.1016/j.stemcr.2013.11.009 DO - 10.1016/j.stemcr.2013.11.009 ID - Liu2014 ER - TY - JOUR AU - Guen, V. J. AU - Chavarria, T. E. AU - Kroger, C. AU - Ye, X. AU - Weinberg, R. A. AU - Lees, J. A. PY - 2017 DA - 2017// TI - EMT programs promote basal mammary stem cell and tumor-initiating cell stemness by inducing primary ciliogenesis and hedgehog signaling JO - Proc Natl Acad Sci U S A VL - 114 UR - https://doi.org/10.1073/pnas.1711534114 DO - 10.1073/pnas.1711534114 ID - Guen2017 ER - TY - JOUR AU - Mani, S. A. AU - Guo, W. AU - Liao, M. J. AU - Eaton, E. N. AU - Ayyanan, A. AU - Zhou, A. Y. PY - 2008 DA - 2008// TI - The epithelial-mesenchymal transition generates cells with properties of stem cells JO - Cell VL - 133 UR - https://doi.org/10.1016/j.cell.2008.03.027 DO - 10.1016/j.cell.2008.03.027 ID - Mani2008 ER - TY - JOUR AU - Marotta, L. L. AU - Almendro, V. AU - Marusyk, A. AU - Shipitsin, M. AU - Schemme, J. AU - Walker, S. R. PY - 2011 DA - 2011// TI - The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(−) stem cell-like breast cancer cells in human tumors JO - J Clin Invest VL - 121 UR - https://doi.org/10.1172/JCI44745 DO - 10.1172/JCI44745 ID - Marotta2011 ER - TY - JOUR AU - Ibrahim, S. A. AU - Gadalla, R. AU - El-Ghonaimy, E. A. AU - Samir, O. AU - Mohamed, H. T. AU - Hassan, H. PY - 2017 DA - 2017// TI - Syndecan-1 is a novel molecular marker for triple negative inflammatory breast cancer and modulates the cancer stem cell phenotype via the IL-6/STAT3, Notch and EGFR signaling pathways JO - Mol Cancer VL - 16 UR - https://doi.org/10.1186/s12943-017-0621-z DO - 10.1186/s12943-017-0621-z ID - Ibrahim2017 ER - TY - JOUR AU - Yen, W. C. AU - Fischer, M. M. AU - Axelrod, F. AU - Bond, C. AU - Cain, J. AU - Cancilla, B. PY - 2015 DA - 2015// TI - Targeting Notch signaling with a Notch2/Notch3 antagonist (tarextumab) inhibits tumor growth and decreases tumor-initiating cell frequency JO - Clin Cancer Res VL - 21 UR - https://doi.org/10.1158/1078-0432.CCR-14-2808 DO - 10.1158/1078-0432.CCR-14-2808 ID - Yen2015 ER - TY - JOUR AU - Yeo, S. K. AU - Wen, J. AU - Chen, S. AU - Guan, J. L. PY - 2016 DA - 2016// TI - Autophagy differentially regulates distinct breast Cancer stem-like cells in murine models via EGFR/Stat3 and Tgfbeta/Smad signaling JO - Cancer Res VL - 76 UR - https://doi.org/10.1158/0008-5472.CAN-15-2946 DO - 10.1158/0008-5472.CAN-15-2946 ID - Yeo2016 ER - TY - JOUR AU - Oskarsson, T. AU - Acharyya, S. AU - Zhang, X. H. AU - Vanharanta, S. AU - Tavazoie, S. F. AU - Morris, P. G. PY - 2011 DA - 2011// TI - Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs JO - Nat Med VL - 17 UR - https://doi.org/10.1038/nm.2379 DO - 10.1038/nm.2379 ID - Oskarsson2011 ER - TY - JOUR AU - Chen, D. AU - Bhat-Nakshatri, P. AU - Goswami, C. AU - Badve, S. AU - Nakshatri, H. PY - 2013 DA - 2013// TI - ANTXR1, a stem cell-enriched functional biomarker, connects collagen signaling to cancer stem-like cells and metastasis in breast cancer JO - Cancer Res VL - 73 UR - https://doi.org/10.1158/0008-5472.CAN-13-1080 DO - 10.1158/0008-5472.CAN-13-1080 ID - Chen2013 ER - TY - STD TI - Zhang H, Fredericks T, Xiong G, Qi Y, Rychahou PG, Li JD, et al. Membrane associated collagen XIII promotes cancer metastasis and enhances anoikis resistance. Breast Cancer Res. 2018;20(1):116. ID - ref20 ER - TY - JOUR AU - Gao, H. AU - Chakraborty, G. AU - Zhang, Z. AU - Akalay, I. AU - Gadiya, M. AU - Gao, Y. PY - 2016 DA - 2016// TI - Multi-organ site metastatic reactivation mediated by non-canonical Discoidin domain receptor 1 signaling JO - Cell VL - 166 UR - https://doi.org/10.1016/j.cell.2016.06.009 DO - 10.1016/j.cell.2016.06.009 ID - Gao2016 ER - TY - STD TI - Yin P, Wang W, Zhang Z, Bai Y, Gao J, Zhao C. Wnt signaling in human and mouse breast cancer: Focusing on Wnt ligands, receptors and antagonists. Cancer Sci. 2018;109(11):3368–75. ID - ref22 ER - TY - JOUR AU - Meyers, S. L. AU - O'Brien, M. T. AU - Smith, T. AU - Dudley, J. P. PY - 1990 DA - 1990// TI - Analysis of the int-1, int-2, c-myc, and neu oncogenes in human breast carcinomas JO - Cancer Res VL - 50 ID - Meyers1990 ER - TY - JOUR AU - Wend, P. AU - Runke, S. AU - Wend, K. AU - Anchondo, B. AU - Yesayan, M. AU - Jardon, M. PY - 2013 DA - 2013// TI - WNT10B/beta-catenin signalling induces HMGA2 and proliferation in metastatic triple-negative breast cancer JO - EMBO Mol Med VL - 5 UR - https://doi.org/10.1002/emmm.201201320 DO - 10.1002/emmm.201201320 ID - Wend2013 ER - TY - JOUR AU - Liu, C. C. AU - Prior, J. AU - Piwnica-Worms, D. AU - Bu, G. PY - 2010 DA - 2010// TI - LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy JO - Proc Natl Acad Sci U S A VL - 107 UR - https://doi.org/10.1073/pnas.0911220107 DO - 10.1073/pnas.0911220107 ID - Liu2010 ER - TY - JOUR AU - Huang, S. AU - Li, Y. AU - Chen, Y. AU - Podsypanina, K. AU - Chamorro, M. AU - Olshen, A. B. PY - 2005 DA - 2005// TI - Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice JO - Genome Biol VL - 6 UR - https://doi.org/10.1186/gb-2005-6-10-r84 DO - 10.1186/gb-2005-6-10-r84 ID - Huang2005 ER - TY - JOUR AU - Harper, K. L. AU - Sosa, M. S. AU - Entenberg, D. AU - Hosseini, H. AU - Cheung, J. F. AU - Nobre, R. PY - 2016 DA - 2016// TI - Mechanism of early dissemination and metastasis in Her2(+) mammary cancer JO - Nature. VL - 540 UR - https://doi.org/10.1038/nature20609 DO - 10.1038/nature20609 ID - Harper2016 ER - TY - JOUR AU - Zhao, K. AU - Wang, Q. AU - Wang, Y. AU - Huang, K. AU - Yang, C. AU - Li, Y. PY - 2017 DA - 2017// TI - EGFR/c-myc axis regulates TGFbeta/hippo/Notch pathway via epigenetic silencing miR-524 in gliomas JO - Cancer Lett VL - 406 UR - https://doi.org/10.1016/j.canlet.2017.07.022 DO - 10.1016/j.canlet.2017.07.022 ID - Zhao2017 ER - TY - JOUR AU - Lee, S. Y. AU - Jeong, E. K. AU - Ju, M. K. AU - Jeon, H. M. AU - Kim, M. Y. AU - Kim, C. H. PY - 2017 DA - 2017// TI - Induction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer cells by ionizing radiation JO - Mol Cancer VL - 16 UR - https://doi.org/10.1186/s12943-016-0577-4 DO - 10.1186/s12943-016-0577-4 ID - Lee2017 ER - TY - JOUR AU - Kannan, A. AU - Krishnan, A. AU - Ali, M. AU - Subramaniam, S. AU - Halagowder, D. AU - Sivasithamparam, N. D. PY - 2014 DA - 2014// TI - Caveolin-1 promotes gastric cancer progression by up-regulating epithelial to mesenchymal transition by crosstalk of signalling mechanisms under hypoxic condition JO - Eur J Cancer (Oxford, England : 1990) VL - 50 UR - https://doi.org/10.1016/j.ejca.2013.08.016 DO - 10.1016/j.ejca.2013.08.016 ID - Kannan2014 ER - TY - JOUR AU - Katoh, M. AU - Katoh, M. PY - 2007 DA - 2007// TI - STAT3-induced WNT5A signaling loop in embryonic stem cells, adult normal tissues, chronic persistent inflammation, rheumatoid arthritis and cancer (review) JO - Int J Mol Med VL - 19 ID - Katoh2007 ER - TY - JOUR AU - Katoh, M. AU - Katoh, M. PY - 2009 DA - 2009// TI - Transcriptional mechanisms of WNT5A based on NF-kappaB, hedgehog, TGFbeta, and Notch signaling cascades JO - Int J Mol Med VL - 23 UR - https://doi.org/10.3892/ijmm_00000190 DO - 10.3892/ijmm_00000190 ID - Katoh2009 ER - TY - JOUR AU - Park, H. W. AU - Kim, Y. C. AU - Yu, B. AU - Moroishi, T. AU - Mo, J. S. AU - Plouffe, S. W. PY - 2015 DA - 2015// TI - Alternative Wnt signaling activates YAP/TAZ JO - Cell VL - 162 UR - https://doi.org/10.1016/j.cell.2015.07.013 DO - 10.1016/j.cell.2015.07.013 ID - Park2015 ER - TY - JOUR AU - Leung, C. AU - Tan, S. H. AU - Barker, N. PY - 2018 DA - 2018// TI - Recent advances in Lgr5(+) stem cell research JO - Trends Cell Biol VL - 28 UR - https://doi.org/10.1016/j.tcb.2018.01.010 DO - 10.1016/j.tcb.2018.01.010 ID - Leung2018 ER - TY - JOUR AU - Plaks, V. AU - Brenot, A. AU - Lawson, D. A. AU - Linnemann, J. R. AU - Kappel, E. C. AU - Wong, K. C. PY - 2013 DA - 2013// TI - Lgr5-expressing cells are sufficient and necessary for postnatal mammary gland organogenesis JO - Cell Rep VL - 3 UR - https://doi.org/10.1016/j.celrep.2012.12.017 DO - 10.1016/j.celrep.2012.12.017 ID - Plaks2013 ER - TY - JOUR AU - Lawson, D. A. AU - Bhakta, N. R. AU - Kessenbrock, K. AU - Prummel, K. D. AU - Yu, Y. AU - Takai, K. PY - 2015 DA - 2015// TI - Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells JO - Nature VL - 526 UR - https://doi.org/10.1038/nature15260 DO - 10.1038/nature15260 ID - Lawson2015 ER - TY - JOUR AU - Flanagan, D. J. AU - Phesse, T. J. AU - Barker, N. AU - Schwab, R. H. AU - Amin, N. AU - Malaterre, J. PY - 2015 DA - 2015// TI - Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5(+) stem cells JO - Stem Cell Reports VL - 4 UR - https://doi.org/10.1016/j.stemcr.2015.03.003 DO - 10.1016/j.stemcr.2015.03.003 ID - Flanagan2015 ER - TY - STD TI - Nile AH, de Sousa EMF, Mukund S, Piskol R, Hansen S, Zhou L, et al. A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nat Chem Biol. 2018;14(6):582–90. ID - ref38 ER - TY - JOUR AU - Martineau, X. AU - Abed, E. AU - Martel-Pelletier, J. AU - Pelletier, J. P. AU - Lajeunesse, D. PY - 2017 DA - 2017// TI - Alteration of Wnt5a expression and of the non-canonical Wnt/PCP and Wnt/PKC-Ca2+ pathways in human osteoarthritis osteoblasts JO - PLoS One VL - 12 UR - https://doi.org/10.1371/journal.pone.0180711 DO - 10.1371/journal.pone.0180711 ID - Martineau2017 ER -