Fig. 3
From: Role of extracellular vesicles in tumour microenvironment
Tumour-derived extracellular vesicles (T-EVs) and their effects on stromal cells. The T-EVs has a variety of effector molecules (including proteins, miRNAs, LncRNAs, and circRNAs), and these molecules are involved in regulation of stromal cells by tumour cells. In addition, there is communication between tumour cells mediated by T-EVs, which many studies have been shown to be associated with cancer resistance and recurrence