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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1α-LIPIN 1 pathway and increasing CD36 through Nrf2

Fig. 1

Increased hepatic steatosis in Sirt3-deficient mice fed a HFD. a, Hematoxylin-eosin staining of livers from male wild-type (WT) and Sirt3−/− mice fed either a standard chow or the HFD were used (n = 6 per group). Scale bar: 20 μm. b, liver triglyceride levels. c, hepatic Fgf21 expression. a, p < 0.05 vs. WT mice fed a standard chow. b, p < 0.05 vs. WT mice fed the HFD. c, p < 0.05 vs. Sirt3−/− mice fed a standard chow

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