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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Repositioning liothyronine for cancer immunotherapy by blocking the interaction of immune checkpoint TIGIT/PVR

Fig. 2

Virtual screening of small molecule compounds from the natural product library targeting PVR. a The structure of PVR from PDB database (PDB ID: 3UDW), with the binding area of TIGIT/PVR interaction labeled in purple, and the binding pocket of compounds identified by MOE labeled in red. b The detail of interacting residues of the binding pocket. c The procedure of screening small molecule compounds targeting PVR

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Cell Communication and Signaling

ISSN: 1478-811X