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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Mitochondrial DNA drives noncanonical inflammation activation via cGAS–STING signaling pathway in retinal microvascular endothelial cells

Fig. 5

Western blotting analysis of phospho-IRF3 (b), TBK1 (c), and NF-κB P65 (d), ICAM1 (e), STING (f) and INF-β (g) in RMECs after stimulation with 1 μg of mtDNA for different times. Western blotting analysis of IRF3 and NF-κB P65 levels in the cytoplasm and nuclei of RMECs after stimulation with 1 μg of mtDNA for different times. h, j, m Amounts of NF-κB P65 and IRF3 in the cytoplasm. k, i, l Amounts of NF-κB P65 and IRF3 in the nuclei. P < 0.01, n = 3 biological repeats in each group

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