Table 1 Secretion or degradation of cargo through an amphisome-dependent mechanism
From: Focus on the morphogenesis, fate and the role in tumor progression of multivesicular bodies
Authors/Years | Cargoes | Cell lines | Amphisome’s judgment | Ref |
|---|---|---|---|---|
Secretion of cargo through an Amphisome-Dependent Mechanism | ||||
Dennis K. Jeppesen et al./2019 | dsDNA and histones | DKO-1, Gli36 | SIM, Colocalization (CD63、LC3) | [13] |
Kaizhe Wang et al./2019 | Autophagy-associated proteins | Hela, MDA-MB-231 | TEM, Colocalization (CD63、LC3) | [38] |
Sandra Atienzar-Aroca et al./2018 | VEGFR2 | ARPE-19 | TEM | [125] |
Georgia Minakaki et al./2018 | SNCA/alpha-synuclein | Human neuroglioma cells | TEM | [120] |
Elisabet Barbero-Camps et al./2018 | Amyloid beta (Ab) | Neuron-rich primary cultures | – | [37] |
Ying-Da Chen et al./2017 | Annexin A2 | Human lung epithelial cells. | Colocalization (CD63、LC3) | [126] |
Nina Pettersen Hessvik et al./2016 | Autophagy-associated protein (NBR1, p62, LC3, WIPI2 etc) | PC-3 | TEM | [64] |
Degration of cargo through an Amphisome-Dependent Mechanism | ||||
Amengual J et al./2018 | Apolipoprotein B100 | Huh7 | Colocalization (EEA1、LC3) | [127] |
Jakob Mejlvang et al./2018 | Autophagy receptors p62/SQSTM1, NBR1, NDP52, NCOA4 | A549, BJ | Immuno-EM (p62), Colocalization (Rab5、LC3) | [63] |
Guodong Wang et al./2017 | Endocytic PEI-Alg NPs | Endothelial progenitor cells | TEM | [128] |
Prasad Tammineni et al./2017 | Association of soluble Aβ oligomers | COS7, | Colocalization (Rab7、LC3) | [129] |
Ruud H. Wijdeven et al./2016 | Cytosolic components | Hela, HEK 293 T | Colocalization (LC3、CD63) | [123] |
Zhihua Chen et al./2016 | Endocytic Ultrafine PM | Human bronchial epithelial cells | TEM | [121] |
Sovan Sarka et al./2013 | Cholesterol | MEF | Colocalization (Rab7、LC3) | [34] |
Yusong Zhang, et al./2012 | Endocytic HMGB1 | HepG2 | Colocalization (HMGB1、LC3) | [122] |