Fig. 3
From: The deubiquitinase USP22 regulates PD-L1 degradation in human cancer cells
USP22 physically interacts with PD-L1. a Co-immunoprecipitation were carried out using either anti-HA or anti-FLAG antibody in HEK293FT cells. b Immunofluorescence staining of endogenous PD-L1 and USP22. Scale bar, 10 μm. c Schematic diagram of PD-L1 and USP22. ECD, extracellular domain; ICD, intracellular domain; TM, transmembrane domain. d The interaction of PD-L1 with fragments of USP22. e The interaction of USP22 with fragments of PD-L1