Skip to main content
Fig. 1 | Cell Communication and Signaling

Fig. 1

From: FBXL6 governs c-MYC to promote hepatocellular carcinoma through ubiquitination and stabilization of HSP90AA1

Fig. 1

FBXL6 is highly expressed in HCC and associated with the c-MYC pathway. a Heatmap demonstrated differentially expressed genes between 374 HCC and 50 non-tumor tissues. b Volcano plot demonstrated differentially expressed genes between 374 HCC and 50 non-tumor tissues. Blue dots represent down-regulated genes and red dots represent up-regulated genes. c The mRNA expression of FBXL6 between 374 HCC and 50 non-tumor tissues. d The GSEA enrichment analysis showed that MYC-targets, bile acid metabolism, fatty acid metabolism and UV response pathways were differentially enriched in patients with high FBXL6 expression. e The GSEA enrichment analysis showed that MYC-targets was enriched in 374 HCC patients with high FBXL6 expression. f The correlation of the mRNAs of FBXL6 and c-MYC in GEPIA website

Back to article page

Cell Communication and Signaling

ISSN: 1478-811X