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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Kinase shRNA screening reveals that TAOK3 enhances microtubule-targeted drug resistance of breast cancer cells via the NF-κB signaling pathway

Fig. 5

Effects of the production of TAOK3 on tumors growth and death after paclitaxel treatments. a The tumor growth curve of Hs578T-VC and Hs578T-TAOK3 with/without paclitaxel (6 mg/kg). Tumor size was calculated by 1/2ab2. b Tumor weight distribution among the four indicative groups. * indicates p < 0.05. c Fluorescence photography of TUNEL stain in Hs578T-VC and Hs578T-TAOK3 cells after treating paclitaxel. d The tumor growth curve of Hcc1806-NS and Hcc1806-shTAOK3 with/without paclitaxel treatment. The treatment was initiated at week 2. “Low dose” refers to 1.1 mg/kg and “high dose” refers to 3.4 mg/kg paclitaxel in each injection. e Tumor weight distribution of the six indicative groups of Hcc1806. * indicates p < 0.05. f Fluorescence photography of TUNEL staining in Hcc1806-NS and Hcc1806-shTAOK3 cells after treatment with paclitaxel

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Cell Communication and Signaling

ISSN: 1478-811X