Fig. 5
From: ERK and Akt exhibit distinct signaling responses following stimulation by pro-angiogenic factors
Predicted maximum pERK and pAkt responses with co-stimulation. Predicted time courses of pERK (a) and pAkt (b) stimulated by the combination of 0.5 nM FGF and 0.5 nM VEGF. Curves are the mean predictions for the 15 best fits from model training. Shaded regions show standard deviation of the fits. Maximum pERK (c) and pAkt (d) in response to co-stimulation by FGF and VEGF for concentrations varying from 0.01 nM to 1 nM