Fig. 4
From: ERK and Akt exhibit distinct signaling responses following stimulation by pro-angiogenic factors
Predicted pERK and pAkt responses stimulated by single agents. a Predicted time courses of pERK and pAkt stimulated by 0.5 nM FGF and 0.5 nM VEGF. Curves are the mean predictions for the 15 best fits from the model training. Shaded regions show standard deviation of the fits. b Maximum pERK (Purple) and pAkt (Green) in response to FGF (left) and VEGF (right) for concentrations varying from 0.01 nM to 1 nM. Bars are mean ± standard deviation of model predictions. Note that the y-axes are not on the same scale