Skip to main content
Fig. 3 | Cell Communication and Signaling

Fig. 3

From: ERK and Akt exhibit distinct signaling responses following stimulation by pro-angiogenic factors

Fig. 3

Model comparison to validation data. a Relative change of pAkt upon stimulation with 10 ng/ml (0.43 nM) FGF compared with reference time point (30 min). b Relative change of Akt phosphorylation upon stimulation with 20 ng/ml (0.44 nM) VEGF compared with reference time point (45 min). c Relative change of VEGFR2 phosphorylation upon stimulation with 80 ng/ml (1.78 nM) VEGF using the reference time point of 7 min. Circles are experimental data from HUVECs. Curves are the mean model predictions of the 15 best fits from the model training. Shaded regions show standard deviation of the fits

Back to article page