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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Correction to: PTH Derivative promotes wound healing via synergistic multicellular stimulating and exosomal activities

Fig. 4

Proliferation of HUVECs (a), HFF-1 cells (b), HaCaTs (c) incubated for 0, 1, 3, or 7 days in conditioned medium with different drug concentrations from days 0 and 6. d Effects of PTHrP-2 on migration of HUVECs, HFF-1 cells and HaCaTs and the tube formation assay of HUVECs. e Quantitation of HUVECs, HFF-1 cells and HaCaTs migration (violet stained cells) using a Transwell chamber. The quantitative evaluation of the number of nodes formed in the culture plate with different drug concentrations after 8 h. f Immunofluorescence images of HUVECs and HFF-1 incubated in each group on day 3. Cytoskeleton and cell nuclei are stained red and blue, VEGF and Collagen I are stained green in the picture taken by the laser scanning confocal microscopy. g VEGF and Collagen I secretion by HUVEC and HFF-1 incubated for 3 days in media with different drug concentrations. h Akt and Erk1/2 phosphorylation level in HUVEC and HFF-1 treated with different drug concentrations

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