Fig. 3

Role of FGF1-mediated glucose metabolism regulation on DICD. a Western blotting and quantitative analysis of FGF1 and FGFR1 expression in the hippocampus from db/m mice, db/db mice and db/db + FGF1-treated mice (n = 3); b The immunofluorescence staining result of FGF1 in the CA1 of hippocampus from mice (Scale bar = 15 μm), n = 3; c Fasting glucose level of mice (n = 10); d and e Blood glucose levels and AUC analysis of mice during GTT (n = 10); f Blood glucose levels of mice during ITT (n = 10); *p < 0.05 vs. db/m mice and db/db + FGF1-treated mice