Fig. 7
From: Regulators of glucose uptake in thyroid cancer cell lines
MYC and HIF-1 regulate glucose metabolism. MYC and HIF-1 are described as important regulators of key genes (in white) involved in glucose uptake and glycolysis pathway control. Abbrevations: Glut1/3, glucose transporter 1 or 3; HK, hexokinase; GPI, glucose phosphate isomerase; PFK-1, phosphofructokinase 1; ALD, aldolase; TI, triose phosphate isomerase; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; PGK, phosphoglycerate kinase; PGAM, phosphoglycerate mutase; ENO, enolase; PKM1/2, pyruvate kinase isoforms 1 and 2; LDHA, lactate dehydrogenase A; G6PDH, glucose 6-phosphate dehydrogenase; GNL, gluconolactonase; 6PDG, 6-phosphogluconate dehydrogenase; MCT1, monocarboxylate transporter-1; HIF-1, hypoxia-inducible factor-1