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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Estrogen-ERα signaling and DNA hypomethylation co-regulate expression of stem cell protein PIWIL1 in ERα-positive endometrial cancer cells

Fig. 5

PIWIL1 and ERα expression in endometrial carcinoma tissues. a Example of PIWIL1 and ERα immunoreactivity in endometrial cancer tissues. Original magnification 200×, scale bar, 100 μm (left); 400×, scale bar, 50 μm (right). b PIWIL1 immunoreactivity scores of 15 ERα-positive endometrial cancer samples and 15 ERα-negative endometrial cancer samples. Values are the mean ± SD. ****p < 0.0001. c A positive correlation was detected between mRNA levels of PIWIL1 and ERα in endometrial cancer samples (r = 0.8, ****p < 0.0001)

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