Skip to main content
Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Suppression of peripheral NGF attenuates neuropathic pain induced by chronic constriction injury through the TAK1-MAPK/NF-κB signaling pathways

Fig. 2

Perisciatic nerve administration of l-CDL suppressed the expression of NGF in the DRG and sciatic nerve of CCI rats. a, b, d, e Immunofluorescence results of intramuscular injection of l-CDL (6 mg/kg) around the sciatic nerve on the operated side of CCI rats showing the expression of NGF in the DRG and sciatic nerve. c The expression of NGF in different types of neurons after l-CDL (6 mg/kg) treatment in CCI rats. f, g Western blotting showing the expression of mNGF and proNGF in the DRG and sciatic nerve after l-CDL (1.5, 3, and 6 mg/kg) treatment of CCI rats. n = 4 per group; ##P < 0.01, and ###P < 0.001, compared with the control group; *P < 0.05, **P < 0.01, and ***P < 0.001, compared with the CCI group

Back to article page

Cell Communication and Signaling

ISSN: 1478-811X