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Table 4 Circular RNAs involved in the regulation of cardiac fibrosis mediated by TGFβ/WNT signaling pathways

From: TGF-β and WNT signaling pathways in cardiac fibrosis: non-coding RNAs come into focus

CircRNAs

Expression (up/down)

Function

model

Anti- fibrotic Pro-fibrotic

Reference

circRNA_010567

Up

Regulated TGF-β signaling and ECM synthesis via sponging up miR-141

Diabetic mice myocardium and CFs

Pro

[178]

CircACTA2

Up

Regulated the expression and function of α-SMA, by acting as a decoy for miR-548f-5p.

TGF-β over-expression increased circACTA2.

Rat, mouse, and human VSMCs

Pro

[13]