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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: PINOT: an intuitive resource for integrating protein-protein interactions

Fig. 5

PINOT and MIST performance comparison for C. elegans PPI data. The performance of PINOT (with stringent and lenient filter options) and MIST was assessed in terms of the number of PPI data entries extracted upon querying different protein lists (on 24th September 2019). The output datasets were evaluated in relation to the number of complete and incomplete (lacking interaction detection method and/or PubMed ID annotations) data entries extracted. The query lists were PD-associated DNAJC orthologs: DNJ-14, DNJ-25, DNJ-27, Y73B6BL.12, K07F5.16, RME-8 and GAKH-1; ATP proteins: ATP-1, ATP-2, ATP-3, ATP-4, ATP-5 and ATP-6; and CED proteins: CED-1, CED-2, CED-3, CED-4, CED-5, CED-6, CED-7, CED-8, CED-9, CED-10, CED-11, CED-12 and CED-13. The input format used for PINOT was the WormBase gene ID, the common gene name (as listed here) was used for MIST querying and no filter by rank parameter was set

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