Cell Communication and Signaling

Table 2 Univariate and multivariate analyses of prognostic factors for 5-year DFS of patients with CRC

From: Effect of CIP2A and its mechanism of action in the malignant biological behavior of colorectal cancer

Variable	Univariate analysis		Multivariate analysis		P
Variable	5 year-DFS	P	HR	CL (95%)	P
Gender		0.190			NS
Female	72.0
Male	74.4
Age		0.989			NS
≥ 65	75.0
< 65	70.6
Location		0.967			NS
Colon	73.0
Rectum	72.8
T stage		0.011			NS
T1-T2	79.2
T3-T4	69.7
N stage		0.002			NS
N0	80.7
N1-N2	61.7
M stage		0.033			NS
M0	73.7
M1	61.6
TNM stage		0.000			0.010
I-II	77.7		1
III-IV	64.7		1.114	0.877–1.414
Histological grade		0.450			NS
Well	77.5
Moderately	72.0
Poorly	69.0
CEA		0.019			0.000
≥ 5	68.0		1
< 5	80.0		0.422	0.271–0.657
CA19–9		0.164			NS
≥ 37	70.0
< 37	79.9
Family history		0.653			NS
No	73.2
Yes	69.2
Liver metastasis		0.000			0.000
No	76.0		1
Yes	13.6		11.129	6.382–6.312
CIP2A		0.007			0.042
Low expression	77.7		1
High expression	63.3		1.478	1.014–2.155

Back to article page

ISSN: 1478-811X

Contact us

General enquiries: journalsubmissions@springernature.com