Effect of CIP2A and its mechanism of action in the malignant biological behavior of colorectal cancer

Table 1 Correlation between CIP2A expression and clinicopathologic characteristics of patients with CRC (n = 390)

Characteristics	Cases	CIP2A protein		P
Characteristics	Cases	Low expression	High expression	P
Gender				0.091
Female	176	97	79
Male	214	136	78
Age				0.838
≥ 65	164	97	67
< 65	226	136	90
Location				0.304
Colon	200	126	74
Rectum	190	110	80
T stage				0.395
T1-T2	106	67	39
T3-T4	284	166	118
N stage				0.253
N0	237	144	93
N1-N2	153	84	69
M stage				0.869
M0	344	205	139
M1	46	28	18
TNM stage				0.010
I-II	227	148	79
III-IV	163	85	78
Histological grade				0.357
Well	47	31	16
Moderately	309	179	130
Poorly	34	23	11
CEA				0.011
≥ 5	161	74	87
< 5	229	135	94
CA19–9				0.057
≥ 37	103	48	55
< 37	287	165	122
Family history				0.291
No	375	224	151
Yes	15	11	4
Liver metastasis				0.291
No	368	220	148
Yes	22	13	9

ISSN: 1478-811X