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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: PTH Derivative promotes wound healing via synergistic multicellular stimulating and exosomal activities

Fig. 2

a 3D reconstructed images showing the new blood vessels; b morphometric analysis of the new blood vessel area and the number of blood vessels. c IHC (Immunohistochemical staining for CD31) and IF (Immunohistochemical staining for CD31+ α-SMA) analysis of neovascularization in wound sites of control, Ca-Alg, PTHrP-2@Ca-Alg groups. The red arrow represents the neovascularization (oval or circular shape). Smooth muscle cells (α-SMA) and EC (CD31) were stained with green, red and blue nuclei. Green and red co-staining represents mature blood vessels. d Quantitative analysis of neovascularization and mature blood vessels at Day 7 and Day 14 post-operation. Micro-CT evaluation of blood vessel formation in diabetic rat treated with different treatment therapies at Day 14 post-surgery

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