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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: Identification of a selective inhibitor of IDH2/R140Q enzyme that induces cellular differentiation in leukemia cells

Fig. 7

CP-17 decreased high level of histone methylation in TF-1(IDH2/R140Q) cells. TF-1(IDH2/R140Q) and TF-1(WT) cells were treated with CP-17 (1 μM, 3 μM) for 7 days, after which expression levels of H3K4Me3, H3K9Me3, H3K27Me3 and H3 were assessed by western blot with specific antibodies. The total amount of H3 was used as loading control

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Cell Communication and Signaling

ISSN: 1478-811X