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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Identification of a selective inhibitor of IDH2/R140Q enzyme that induces cellular differentiation in leukemia cells

Fig. 5

CP-17 treatment reversed GM-CSF-independent growth induced by IDH2/R140Q. IDH2/R140Q expression confers GM-CSF independent growth of the TF-1 cells. Proliferation of TF-1(IDH2/R140Q) (a) and TF-1(WT) (b) cells with the treatment of CP-17. (* P < 0.01 vs 7 day of Control, #P < 0.01 vs 0 day of Control). The variance is similar between the groups that are being statistically compared

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Cell Communication and Signaling

ISSN: 1478-811X