The role of CSDE1 in translational reprogramming and human diseases

Table 2 The components and function of CSDE1 in the “Protein-RNA connector” model

Connection models	Protein regulators	RNA	CSDE1 function	Reprogramming directions	Cells	References
Sequential	Unrip	BC200	RNA stability	↑	MCF-7	[64]
Mutual	SXL	Msl-2	Translation	↓	Drosophila female	[14, 69, 70]
	IMP1,PABP	PABP	Translation	↓	HeLa	[51, 54]
	PABP, PAIP-1, hnRNP D, NSAP1	c-fos	RNA stability	↑	NIH3T3; HeLa	[62]
Facilitate	PTB	Apaf-1	Translation	↑	COS7, MRC5, SY5Y, BALB/c	[11]
	PTB	HRV-2	Translation	↑	HeLa	[42]
	PTB	CSDE1	Translation	↓	Mouse ES	[48]

ISSN: 1478-811X