The role of CSDE1 in translational reprogramming and human diseases

Table 1 Reprogramming role of CSDE1 in biological processes and diseases

Biological processes and diseases	The role of CSDE1	References
Biological processes
Cell cycle	Promotion	[10]
Apoptosis	Promotion	[11]
Differentiation	Repression	[12]
Dosage compensation (male)	Promote DCC assembly	[14]
Dosage compensation (female)	Repress DCC formation	[13]
Tumors
Melanoma	Oncogene	[15]
Colorectal cancer	Oncogene	(98)
Glioma	Oncogene	[16]
Breast cancer	Oncogene	[17]
PCCs &PGLs	Tumor suppressor	[18]
Oral squamous cell carcinoma	Tumor suppressor	[19]
Pancreatic ductal adenocarcinoma	Prognostic biomarker	[20]
Epithelial ovarian cancer	Platinum resistance gene	[21]
Other diseases
Autism spectrum disorder	Loss of function mutation	[22]
Diamond-Blackfan anemia	Low expression	[23]
Embryonic development	Prevent ESC differentiation	[24, 25]

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