Table 1 Univariate and multivariate analysis of OS in CGGA RNA sequencing dataset, GBM patients wtith chemotherapy

Risk score

2.533 (1.348–4.760)

0.004

2.578 (1.217–5.462)

0.013

Age at diagnosis

1.001 (0.974–1.028)

0.954

–

–

Gender

0.675 (0.353–1.293)

0.236

–

–

TCGA subtype

1.014 (0.789–1.304)

0.912

–

–

MGMT promoter status

0.539 (0.295–0.985)

0.045

0.759 (0.393–1.463)

0.410

IDH mutation status

0.657 (0.325–1.328)

0.242

–

–

Radiotherapy

0.303 (0.157–0.584)

< 0.001

0.759 (0.393–1.463)

< 0.001