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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: The let-7 family of microRNAs suppresses immune evasion in head and neck squamous cell carcinoma by promoting PD-L1 degradation

Fig. 1

The expression of let-7 family of miRNAs is reduced in HNSCC, and let-7 family of miRNAs is related to PD-L1 expression. a the expression of let-7 family of miRNAs in HNSCC examined by RT-qPCR. b the relationship between let-7a/7b and prognosis of patients analyzed by Kaplan Meier survival analysis. c PD-L1 stains (× 400) in HNSCC tissues and adjacent normal tissues examined by immunohistochemistry. d the relationship between the PD-L1 expression in HNSCC examined by western blot analysis and the let-7a/7b expression in HNSCC examined by RT-qPCR. * p < 0.05 compared with the control group. The results were measurement data and were expressed as mean ± standard deviation. The results in Fig. 1a were analyzed by paired t test. N = 37. HNSCC, squamous cell carcinoma of the head and neck; RT-qPCR, reverse transcription quantitative polymerase chain reaction; PD-L1, programmed death-ligand 1. Each experiment was conducted at least three times

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Cell Communication and Signaling

ISSN: 1478-811X