Group | IL-4 | IL-10 | IL-17 | INF-γ | ||||
---|---|---|---|---|---|---|---|---|
0 W (n = 10) | 24 W (n = 10) | 0 W (n = 10) | 24 W (n = 10) | 0 W (n = 10) | 24 W (n = 10) | 0 W (n = 10) | 24 W (n = 10) | |
Control | 9.24 ± 3.0 | 9.52 ± 2.01 | 30.12 ± 7.58 | 34.98 ± 8.14 | 8.73 ± 2.41 | 7.51 ± 2.50 | 11.93 ± 0.78 | 11.33 ± 1.37 |
VDR−/− | 9.70 ± 3.14 | 20.55 ± 4.18*$ | 36.12 ± 7.04 | 79.39 ± 7.30*$ | 8.45 ± 1.47 | 13.95 ± 2.68*$ | 12.29 ± 4.77 | 23.65 ± 5.12*$ |
SLE | 35.80 ± 6.02* | 38.39 ± 2.56* | 82.08 ± 13.35* | 90.44 ± 10.83* | 15.76 ± 3.83* | 16.27 ± 3.10* | 29.92 ± 7.81* | 32.67 ± 4.58 |
SLE + VD3 | 34.71 ± 3.64* | 12.27 ± 3.55#$ | 83.27 ± 11.44* | 43.74 ± 4.83#$ | 15.60 ± 2.96* | 9.77 ± 5.28#$ | 28.71 ± 5.10* | 14.94 ± 3.13*#$ |
SLE + VD3 + VDRinsert | 34.14 ± 3.11* | 11.79 ± 1.84#$ | 81.59 ± 9.20* | 41.69 ± 5.18#$ | 15.02 ± 3.62* | 8.40 ± 2.02#$ | 28.62 ± 2.72* | 14.32 ± 2.11#$ |