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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: 1,25-(OH)2D3/Vitamin D receptor alleviates systemic lupus erythematosus by downregulating Skp2 and upregulating p27

Fig. 2

1,25(OH)2D3 and VDR are negatively correlated with Skp2 and positively correlated with p27 in SLE patients. a comparison of the 1,25-(OH)2D3 content in incipient SLE patients and healthy controls. b mRNA expression of VDR, p27 and Skp2. c correlation between 1,25(OH)2D3 and Skp2 expression. d correlation between 1,25(OH)2D3 and p27 expression. e correlation of VDR and Skp2 expression. f correlation between VDR and p27 expression. n = 149 for SLE patients and n = 150 for healthy controls; the independent sample t-test was performed to analyze data; * p < 0.05 vs. the healthy controls; VDR, vitamin D receptor; Skp2, S-phase kinase-associated protein 2; SLE, systemic lupus erythematosus

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