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Fig. 12 | Cell Communication and Signaling

Fig. 12

From: 1,25-(OH)2D3/Vitamin D receptor alleviates systemic lupus erythematosus by downregulating Skp2 and upregulating p27

Fig. 12

1,25-(OH)2D3/VDR downregulates the Skp2 expression and upregulates the p27 expression in SLE mice. a the mRNA expression of Skp2 and p27 determined by RT-qPCR. b the protein expression of Skp2 and p27 measured by western blot analysis. c the statistical analysis of panel B; n = 20, one-way analysis of variance was used to analyze data; * p < 0.05 vs. the control group; # p < 0.05 vs. the SLE group; Skp2, S-phase kinase-associated protein 2; SLE, systemic lupus erythematosus; RT-qPCR, reverse transcription quantitative polymerase chain reaction

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